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Id have to say that the most affective weapon in halo is the plasma rifle. But Its only the most affective when your playing against the covenant. When your playing against your friends or whoever it has to be the pistol.For halo 2 its hard to say but im pretty sure that the new covenant rifle will be the best in the campain mode. For halo 2 and Xbox live its probably going to be the pistol again or the new asault rifle.
or that bomb that detroys what you tell it too jk,,,In campian mode i always use pistol and in MP i always use the pistol its my fav
im all sniper... halo and halo2