I just had my first non-practice run at LNOS today (had been doing runs sans blind and iron), completed with two deaths. Annoying thing is they were both stupid deaths, not on any of the hard parts I was expecting I might die on, but just my own stupid mistakes.
Beem elites got me while I was trying to head back into the door to safety, after nabbing the Engineer at the start of the hanger... I badly mistimed my use of the dropshield. 2nd death was just being annoyed/reckless because of the first.
All went well after that. Gun room guys were awake upon entry, but at least they were both plasma riflers, no concussion. Wasn't able to assasinate everyone on the bridge, but was able to get the big bad then run back to safety and take out the rest with not too much trouble.
Well, next time hopefully... doubt it though, heh. I get the feeling that something will always go wrong.
I am enjoying the door opening bit after the cutscene when Jorge joins us: I grab the concussion, shoot its crate towards the door, and go nuts at it when the door opens. I think I splattered one of the two elites in there with that. Tried to do the same on the door after I press the button on the bridge, but didnt get close enough to fire a good shot quick enough.
[Edited on 04.21.2011 3:33 AM PDT]