We kill that which we do not understand...and then promptly tea-bag it.
The scene in Halo:First Strike when Admiral Whitcomb and Lt. Haverson stay aboard Ascendant Justice and fight to the death...as the scene pans out on the video, the Unyielding Hierophant explodes, and takes out that entire Covenant armada. Also, in Ghosts of Onyx, when Kwassass, the Unggoy, goes to the N.O.V.A. bomb and plays its message...I am Vice Admiral Danforth Whitcomb, temporarily in command of the UNSC base Reach. To the Covenant uglies that might be listening, you have a few seconds to pray to your damned heathen gods..."(p. 239). The ironic part is how at first Kwassass is squealing in delight at the sounds, then realizes that its a bomb and rushes to defuse it, but the Huragok are too busy trying to turn it back ON...and then a bright white light...:D I'm not sure if those are my ALL TIME favorites, but they're definitely epic moments. Oh, ya, forgot about the my favorite game moments...let's see, how 'bout when MC beats the living be-jeebus out of Regret, gets the hell out of there as the place is plasma bombarded, and then *gasp* meets the "monument to all his sins" (words cannot describe that scene well enough).
[Edited on 07.26.2011 11:13 AM PDT]