Halsey would probably just be somber about it, but ultimately, it may somehow influence her actions. (relatively speaking)
Speaking of the Keyes family, I think it'd be a nice little nod to the tradition of having the primary commanding character be a member of the same family, i.e., having Halsey take on the role Jacob (CE) and Miranda (2-3) played.
[Edited on 07.27.2011 6:30 PM PDT]